EI

What if We Could Prevent A Heart Attack from Happening?


Nanophagix is developing a unique therapeutic delivery system that lets doctors treat the major cause of heart attacks directly at the source.

Potential Breakthrough Technology:

heartCT image of rabbit heart 1
  • NanoPhagix has combined the delivery mechanism of a nanoparticulate imaging agent with rapamycin to deliver a potent anti‑inflammatory directly to multiple sites of vascular inflammation.
  • This unique formulation allows for selective delivery to unstable plaque areas and enables safer targeting of the drug to sites of need.
  • Rapamycin is an approved anti‑inflammatory drug previously shown to have a wide variety of cardiovascular benefits.

NanoPhagix is developing a unique therapeutic delivery system designed to let doctors treat the major cause of heart attacks directly at the source.

By leveraging its expertise in nanotechnology, rapamycin, molecular biology, and atherosclerosis, NanoPhagix is committed to developing "next generation" targeted therapeutics employing rapamycin for cardiovascular conditions as well as other therapeutic categories in which inflammation is the underlying cause.

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References

1 Fabien Hyafil, Jean-Christophe Cornily, Jonathan E Feig et al,"Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography",Nature Medicine 13, 636 - 641 (2007), Published online: 8 April 2007.